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Iterative Health · Operations · Lead / Manager · Posted 2026-09-24

Senior Director, Medical Affairs - Cardiology

Iterative Health · NYC, Cambridge or Southlake HQ · $210k–265k base

This range's midpoint is above 78% of posted operations ranges at AI companies right now. See the salary index.

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Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes.

We built a leading performance-driven network of 100+ sites across the US, Europe, India, and Australia, conducting research directly in the communities where care is delivered across gastrointestinal, hepatology, obesity, and cardiology. By combining deep clinical trial expertise with cutting-edge AI, we connect sponsors' scientific ambitions with high-performing research teams that expedite and expand access to novel therapeutics for patients in need. Today, Iterative Health is headquartered in Cambridge, Massachusetts, and New York City with 250+ employees world-wide.

We’re hiring a strategic and relationship-driven Senior Director of Medical Affairs to lead how we engage, educate, and influence Principal Investigators (PIs) across our growing site network

In this role, you’ll build trusted peer-to-peer relationships with physicians, site leads, and clinical decision-makers. You’ll be responsible for helping PIs understand and embrace Iterative Health’s trial model, clinical philosophy, and performance standards - ensuring consistency, trust, and long-term site engagement across the network.

You’ll serve as a clinical ambassador and influencer, working cross-functionally with product,

site operations, and corporate development to shape how we scale, support, and activate high-performing sites. This is a high-impact, field-driven leadership role with strategic scope and visibility

The ideal candidate brings strong clinical and scientific credibility, exceptional relationship-building skills, and the ability to operate strategically in a fast-paced, highly collaborative healthcare environment.

Where You’ll Drive Impact 

Physician Engagement 

Establish and deepen relationships with PIs and site leadership across our cardiology sites

Develop and foster a structured engagement strategy with top investigators in the network 

Communicate Iterative Health’s clinical philosophy, trial model, and standards of excellence to site physicians

Partner closely with Site Operations, Corporate Development, and Life Sciences teams to develop evidence-generation strategies.

Evaluate emerging scientific literature, clinical trends, standards of care, and competitive developments.

Translate complex clinical and scientific findings into clear strategic and clinical operational recommendations for PIs, leadership,  and external partners.

Serve as a strategic medical partner to CV Site Operations, Life Sciences, Corporate Development, Marketing, and executive leadership.

Provide insight into site capabilities, performance, and interest areas to help shape the trial portfolio at the site level

Support site growth by collaborating with Corporate Development to assess and engage new site leads

Partner with Business Development to support protocol evaluations with current and prospective life sciences customers.

Work closely with Clinical Operations and Site Network leadership to incorporate investigator and site perspectives into clinical strategy.

Provide medical expertise in support of new indications, partnerships, acquisitions, and strategic initiatives.

Performs related duties as requested 

What You Bring to the Team 

MD, DO, PharmD, PhD, or equivalent advanced degree in a relevant medical or scientific discipline.

10+ years of relevant experience in Medical Affairs, Field Medical, Site Engagement,  at a biotechnology or pharmaceutical company. 

Significant experience with cardiology principal investigators, community research sites, and cardiology KOLs

Proven ability to build trust with physicians and influence clinical behavior

Track record of driving site engagement and performance in clinical trials

Strong understanding of clinical research, evidence generation, clinical development, and the healthcare ecosystem.

Exp …

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